The rise of digital misinformation has heightened interest in using multilingual Large Language Models (LLMs) for fact-checking. This study systematically evaluates translation bias and the effectiveness of LLMs for cross-lingual claim verification across 15 languages from five language families: Romance, Slavic, Turkic, Indo-Aryan, and Kartvelian. We investigate two distinct translation methods—pre-translation and self-translation—using the XFACT dataset to assess their impact on accuracy and bias. As a baseline, we use mBERT’s performance on the English dataset to compare language-specific accuracies. Our findings reveal that low-resource languages exhibit significantly lower accuracy in direct inference due to underrepresentation in the training data. Furthermore, larger models demonstrate superior performance in self-translation, improving translation accuracy and reducing bias. These results highlight the need for balanced multilingual training, especially in low-resource languages, to promote equitable access to reliable fact-checking tools and minimize the risk of spreading misinformation in different linguistic contexts.