The Machine Learning Meets Econometrics (MLECON) workshop will serve as an interface for researchers from machine learning and econometrics to understand challenges and recognize opportunities that arise from the synergy between these two disciplines as well as to exchange new ideas that will help propel the fields. Our one-day workshop will consist of invited talks from world-renowned experts, shorter talks from contributed authors, a Gather.Town poster session, and an interdisciplinary panel discussion. To encourage cross-over discussion among those publishing in different venues, the topic of our panel discussion will be “Machine Learning in Social Systems: Challenges and Opportunities from Program Evaluation”. It was designed to highlight the complexity of evaluating social and economic programs as well as shortcomings of current approaches in machine learning and opportunities for methodological innovation. These challenges include more complex environments (markets, equilibrium, temporal considerations) and behavior (heterogeneity, delayed effects, unobserved confounders, strategic response). Our team of organizers and program committees is diverse in terms of gender, race, affiliations, country of origin, disciplinary background, and seniority levels. We aim to convene a broad variety of viewpoints on methodological axes (nonparametrics, machine learning, econometrics) as well as areas of application. Our invited speakers and panelists are leading experts in their respective fields and span far beyond the core NeurIPS community. Lastly, we expect participants with diverse backgrounds from various sub-communities of machine learning and econometrics (e.g., non- and semi-parametric econometrics, applied econometrics, reinforcement learning, kernel methods, deep learning, micro- and macro-economics) among other related communities.