Since Hebb articulated his Neurophysiological Postulate in 1949 up to the present day, the relationship between synapse modification and neuronal activity has been the subject of enormous interest. Laboratory studies have revealed phenomena such as LTP, LTD, and STDP. Theoretical developments have both inspired studies and been inspired by them. The intent of the proposed workshop is to foster communication among researchers in this field. The workshop is intended to be of interest to experimentalists and modelers studying plasticity from the neurobiological level to the cognitive level. The workshop is targeted toward researchers in this area, hopefully drawing a 50/50 mix of experimental results and theoretical ideas. Another goal is to bring together established researchers with grad students and postdocs.